Patrick Soon-Shiong

Chinese-American billionaire physician, CEO & philanthropist

The drug Abraxane, used for lung, breast, and pancreatic cancer, was invented by Patrick Soon-Shiong, a surgeon and entrepreneur whose career spans biotechnology and healthcare media. Born in 1952 in Gqeberha, South Africa, he established a diverse portfolio of businesses, including a network of startups under the NantWorks umbrella and a position as owner of the Los Angeles Times.

Medical Education and Surgical Training

Soon-Shiong attended the University of the Witwatersrand, where he earned a Bachelor of Medicine and an M.D. After completing an internship at Johannesburg's General Hospital, he moved to the University of British Columbia to obtain a master's degree in surgery in 1979. He later immigrated to the United States to pursue surgical training at the University of California, Los Angeles, becoming a board-certified surgeon in 1984.

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Academic and Research Contributions

From 1983 to 1991, Soon-Shiong served on the faculty at UCLA Medical School, where he performed the institution's first whole-pancreas transplant. His experimental work included encapsulated-human-islet transplants for Type 1 diabetes and early pig-to-man islet-cell procedures. He returned to UCLA in 2009 as a professor of microbiology, immunology, molecular genetics, and bioengineering, and has held visiting professorships at Imperial College London and Dartmouth College.

Biotechnology and Pharmaceutical Development

As the founder of NantWorks, Soon-Shiong oversees a network focused on artificial intelligence and healthcare. His pharmaceutical development work culminated in the FDA approval of Anktiva, an immunotherapy drug for non-muscle invasive bladder cancer, in 2024. Through ImmunityBio, he has led clinical trials on the use of IL-15 superagonists to treat lymphopenia and stimulate natural killer cell proliferation in patients with solid tumors.

Philanthropy and Public Policy

Soon-Shiong chairs the Chan Soon-Shiong Family Foundation. His public policy work includes a 2017 appointment to the Health Information Technology Advisory Committee. In 2021, he launched NantSA to expand vaccine development capabilities in Sub-Saharan Africa. He holds various accolades for his work, including the 2016 Bower Award for Business Leadership and the Benjamin Franklin Medal.

Fast facts

Questions readers ask

What medical conditions does Anktiva treat?

Anktiva is FDA-approved for non-muscle invasive bladder cancer and is being studied for its role in immune reconstitution for patients with solid tumors.

Which major newspaper does Patrick Soon-Shiong own?

He has been the owner and executive chairman of the Los Angeles Times since 2018.

Achievements

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