Archiv für die gesammte Physiologie des Menschen und der Thiere, established by Eduard Pflüger in 1868, evolved into the most influential physiology journal in Germany. His career spanned decades of transformative medical research, bridging the transition from early biological investigation to the more rigorous, evidence-based physiological standards that eventually defined modern medical practice and academic training.
Early Education and Professional Beginnings
Born on 7 June 1829 in Hanau, Pflüger initially pursued legal studies at Berlin University. He eventually transitioned to medicine, undertaking academic work at the Humboldt-Universität zu Berlin and the University of Marburg. During his time in Berlin, he served as an assistant to Emil du Bois-Reymond. In 1853, he earned his doctorate, marking the start of a long career dedicated to the systematic study of human and animal physiology.
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In 1859, Pflüger accepted a position as a professor of physiology at the University of Bonn. He remained at this institution for the duration of his professional life, mentoring numerous students who later achieved distinction in their own fields, including the physiologist Nathan Zuntz and the chemist Hugo Paul Friedrich Schulz. His work in Bonn encompassed diverse areas, such as the sensory functions of the spinal cord, protein metabolism, intestinal peristalsis, and the regulation of body temperature.
Scientific Discoveries and Research Output
Pflüger is remembered for his investigations into electrophysiology, most notably the development of 'Pflüger's law,' which relates electrical stimulation to muscular contraction. He significantly advanced the understanding of respiration by proving that gas exchange occurs within peripheral tissues rather than in the blood. Additionally, his research into glycogen and his extensive list of publications—ranging from texts on psychiatry and neurasthenia to specialized studies on muscle strength and diabetes—cemented his status as a key contributor to 19th-century science.
Recognition and Legacy
Throughout his life, Pflüger attained membership in numerous prestigious institutions, including the Royal Society, the Russian Academy of Sciences, and the Royal Prussian Academy of Sciences. In 1888, he became a Foreign Member of the Royal Society. By 1909, he was named an honorary citizen of Bonn and received the Pour le Mérite for Sciences and Arts order. He died in Bonn on 16 March 1910 and is buried at the Poppelsdorf Cemetery.
Fast facts
- Born: 7 June 1829, Hanau
- Died: 16 March 1910, Bonn
- Education: University of Marburg and Humboldt-Universität zu Berlin
- Primary Employer: University of Bonn
- Notable Work: Archiv für die gesammte Physiologie des Menschen und der Thiere
- Awards: Foreign Member of the Royal Society, Pour le Mérite for Sciences and Arts
- Burial Site: Poppelsdorf Cemetery
Questions readers ask
What is Pflüger's law?
It is a scientific principle detailing the correlation between electrical stimulation and muscular contraction.
Where did Pflüger conduct his most significant research?
He performed the majority of his academic and research work at the University of Bonn, where he held a professorship from 1859 until his death.
Achievements
- Held posts at University of Bonn

