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🇺🇸Grace
Sun

Bioelectronics Innovator · Regeneron ISEF 2024 Grand Prize
$75,000 George D. Yancopoulos Innovator Award · Age 16
Paul Laurence Dunbar High School, Lexington, Kentucky

Grace Sun, Regeneron ISEF 2024 Grand Prize Winner

Fast Facts

Born
c. 2007
Hometown
Lexington, Kentucky, USA
School
Paul Laurence Dunbar HS
Field
Bioelectronics
Top Award
$75,000 ISEF Grand Prize
Year Won
2024 (Age 16)
Innovation
Organic Electrochemical Transistor
Potential Impact
Epilepsy, Diabetes, Organ Failure

Los Angeles, May 17, 2024. The Grand Awards Ceremony of the Regeneron International Science and Engineering Fair fills a convention hall with nearly two thousand of the world's most gifted young scientists. Names are read. Awards mount. And then the moment the entire room has been waiting for: the $75,000 George D. Yancopoulos Innovator Award — the single highest prize the fair bestows. It goes to a sixteen-year-old from Lexington, Kentucky. Her name is Grace Sun, and her research just changed what the scientific community believes is possible inside the human body.

Grace's project focused on organic electrochemical transistors, or OECTs — tiny electronic devices with enormous medical potential. Unlike the rigid silicon chips that power our computers, OECTs are soft, flexible, and biocompatible, meaning they can, in theory, be placed inside the human body. They could detect the onset of a diabetic episode, sense an epileptic seizure seconds before it strikes, or monitor the health of a failing organ in real time. The problem — and it is a formidable one — is that OECTs have historically struggled to perform reliably once introduced to the wet, chemically complex environment of living tissue. The performance degrades. The promise goes unfulfilled.

Grace identified the specific failure mode: the organic components of the transistors were not chemically stable under biological conditions. Working in a high school lab with a rigor that would impress most university research teams, she developed a novel chemical treatment process — a way of modifying the organic layer of the transistor so that it maintains its performance far longer than previous designs. Her treated transistors outperformed untreated controls by a dramatic margin in laboratory testing conditions designed to simulate the body's interior environment.

"This was our number one project, without a shadow of a doubt. The judges were unanimous."

— Ian Jandrell, ISEF Materials Science Judging Co-Chair, May 2024

The judging panel's reaction was categorical. Ian Jandrell, co-chair of the materials science category, told reporters that there had been no debate — Grace's project was the unanimous choice at the top of the pile. In a fair with finalists from sixty-seven countries, territories, and regions, each having won their regional competition to earn a place in Los Angeles, that kind of consensus is extraordinary. Grace had not just won a science fair. She had impressed career researchers who work in adjacent fields professionally.

Grace grew up in Lexington, a city better known for horses and bourbon than for producing bioelectronics researchers. She attended Paul Laurence Dunbar High School, named for the African American poet, and was a junior when she entered her project. Those who know her describe a student who combines sharp curiosity with methodical discipline — the kind of person who does not just ask why something doesn't work, but builds a systematic plan to fix it. Her ISEF project was the culmination of months of research and iterations, not a lucky insight from a single afternoon.

Her work sits at the intersection of materials science, chemistry, and medicine — three disciplines that rarely talk to each other at the secondary school level, let alone get integrated into a single coherent research program. Grace navigated all three. She understood not just what she was building, but why each chemical decision mattered, and how it mapped onto the eventual goal: a device that could survive inside a human body long enough to be medically useful. That systems-level thinking is what set her work apart from other strong finalists.

"I want these devices to actually help people — that's the whole point. Not just to work in a lab, but to work inside a patient."

— Grace Sun, post-award interview, Regeneron ISEF 2024

The implications of her research extend in multiple directions. Epilepsy affects approximately fifty million people worldwide, and a reliable implantable seizure-detection device could transform patients' lives. Diabetes management, currently dependent on fingerpricks or external sensors, could be revolutionized by a long-lasting internal monitor. And for patients with failing organs waiting for transplants, a real-time monitoring device could save lives by alerting surgeons before a crisis becomes irreversible. Grace did not build any of those devices. But she may have removed one of the central obstacles standing in the way of people who will.

With $75,000 in prize money and the scientific credibility of the world's most prestigious high school science competition behind her, Grace Sun enters the university research world not as a promising student but as a proven innovator. The question now is not whether she will make an impact on biomedical science. It is only how large that impact will be.

Achievement Timeline

2021–22
Early Research Begins Starts systematic investigation of organic electronic materials at Paul Laurence Dunbar High School, identifying biocompatibility as the critical unsolved problem in OECT design.
2023
Chemical Treatment Breakthrough Develops novel surface treatment protocol for OECT organic layers, achieving dramatically improved stability under simulated biological conditions compared to all previous published designs.
2024 (Spring)
Regional ISEF Qualifier Win Wins regional science fair competition in Kentucky, earning a place as one of approximately 1,700 finalists selected globally to compete at Regeneron ISEF in Los Angeles.
2024 (May 16)
Special Awards at ISEF Collects special category awards on the first awards night, foreshadowing the grand prize to follow the next morning.
2024 (May 17)
$75,000 Grand Prize — George D. Yancopoulos Innovator Award Wins the top award at Regeneron ISEF 2024, the most prestigious science competition for high school students in the world, selected unanimously by the judging panel from among 1,700 global finalists.
2024–25
University Research Pathway Graduates Dunbar High School and moves toward university-level biomedical engineering research, carrying foundational OECT work into the next stage of development.

ISEF Grand Prize Winners: A Generation of Science

Year Winner Country Field Age
2021 Arnav Kapur India/USA Neurotechnology 17
2022 Vivien Roussel France Environmental Science 17
2023 Yiheng Xu USA Materials Science 17
2024 Grace Sun USA 🇺🇸 Bioelectronics 16

Bioelectronics & ISEF 2024

Regeneron ISEF 2024 — Grand Awards Ceremony (Society for Science)

Organic electrochemical transistors — science behind the breakthrough

Why This Matters

The gap between a brilliant idea for a medical implant and a device that actually works inside the human body is enormous — and most of that gap is a materials problem. Organic electronics that degrade inside the body are devices that never make it to patients. Grace Sun, at sixteen years old, attacked one of the central failure modes of implantable bioelectronics and produced a measurable improvement. She did not do this at MIT or Stanford or Caltech. She did it at a high school in Kentucky, with high-school resources, driven by nothing more than curiosity and the conviction that the problem was solvable. The fifty million people living with epilepsy, the hundreds of millions managing diabetes, and the countless patients with failing organs who wait and hope — they do not know Grace Sun's name yet. They may one day.

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